Rotavirus vaccine and human papilloma vaccine.

Rotavirus is the chief cause of diarrhoea in infants and toddlers ,accounting for about 6 - 45 % of diarrhoea related hospitalization in Indian children . Natural infection does not protect against reinfection or severe disease. The first licensed vaccine ( rotashield) , a live oral tetravalent vaccine, was withdrawn following an association with intussucception.  Another world wide vaccine is rotatrix .

   Rotateq is pentavalent vaccine with 2-116 million infectious units each of the strains (G1-4  and P8) reassorted between bovine and human wc3 virus and attenuated by Vero cell culture. Rotavac is an indigenous monovalent human bovine recombinant vaccine based on G9 P11 or 116E strain manufactured in India .. given its importance , rotavirus vaccination was introduced in four states( Andra Pradesh ,Himachal Pradesh , Haryana and Odisha ) using the
rotavac vaccine. 

Human papilloma virus 

  

Cervical cancer , the second most common cancer in human , is almost always due to infection with oncogenic HPV belonging to 20 - 100 known serotypes. Government of Delhi and Punjab have initiated school based programmes for girls aged 11 -13 years old since 2016. Elsewhere ,IAP recommends  that vaccine is offered to all girls prior to sexual debut . Immunization carries risk of complacency regarding routine screening for cancer ,which together with incomplete immunization coverage might paradoxically raise cervical cancer related mortality .There are no serious adverse events of HPV vaccine .

Hope this finds you all interesting  and helpful enough .